BDBM50012539 CHEMBL3260763

SMILES: COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccc(C)cn2)cc1

InChI Key: InChIKey=JUNABFZCPAWJPC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50012539 (CHEMBL3260763) Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccc(C)cn2)cc1 Show InChI InChI=1S/C26H24N2O6S/c1-17-4-13-25(27-15-17)35(30,31)28-26(29)24-14-21(18(2)34-24)16-33-23-11-7-20(8-12-23)19-5-9-22(32-3)10-6-19/h4-15H,16H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting				Bioorg Med Chem Lett 24: 2212-21 (2014) Article DOI: 10.1016/j.bmcl.2014.02.068 BindingDB Entry DOI: 10.7270/Q2125V6J
					More data for this Ligand-Target Pair