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BDBM50012543 CHEMBL3260767

SMILES: Cc1noc(C)c1S(=O)(=O)NC(=O)c1cc(COc2ccc(cc2)-c2ccc(OC(F)F)cc2)c(C)o1

InChI Key: InChIKey=QFCQOXTUIKVTDA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012543   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50012543
PNG
(CHEMBL3260767)
Show SMILES Cc1noc(C)c1S(=O)(=O)NC(=O)c1cc(COc2ccc(cc2)-c2ccc(OC(F)F)cc2)c(C)o1
Show InChI InChI=1S/C25H22F2N2O7S/c1-14-23(16(3)36-28-14)37(31,32)29-24(30)22-12-19(15(2)34-22)13-33-20-8-4-17(5-9-20)18-6-10-21(11-7-18)35-25(26)27/h4-12,25H,13H2,1-3H3,(H,29,30)
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.600n/an/an/an/an/an/an/an/a



Argenta Discovery Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting


Bioorg Med Chem Lett 24: 2212-21 (2014)


Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J
More data for this
Ligand-Target Pair