BDBM50012545 BGC-201531::CHEMBL1628698
SMILES: COc1ccc(nc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2C)cc1
InChI Key: InChIKey=IXDVRRPNWPOPGV-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50012545 (BGC-201531 | CHEMBL1628698) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd. Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting | Bioorg Med Chem Lett 24: 2212-21 (2014) Article DOI: 10.1016/j.bmcl.2014.02.068 BindingDB Entry DOI: 10.7270/Q2125V6J | |||||||||||
More data for this Ligand-Target Pair |