BDBM50012827 10H-Phenoxazine::CHEMBL276850::PHENOXAZINE

SMILES: N1c2ccccc2Oc2ccccc12

InChI Key: InChIKey=TZMSYXZUNZXBOL-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50012827 (10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE) Show SMILES N1c2ccccc2Oc2ccccc12 Show InChI InChI=1S/C12H9NO/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-lipoxygenase in vitro (guinea pig PMN)				Bioorg Med Chem Lett 1: 107-110 (1991) Article DOI: 10.1016/S0960-894X(00)80241-3 BindingDB Entry DOI: 10.7270/Q2DF6R3J
					More data for this Ligand-Target Pair
Tubulin beta chain (Sus scrofa)	BDBM50012827 (10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE) Show SMILES N1c2ccccc2Oc2ccccc12 Show InChI InChI=1S/C12H9NO/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Westphalian Wilhelms-University Curated by ChEMBL					Assay Description Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysis				J Med Chem 54: 4247-63 (2011) Article DOI: 10.1021/jm200436t BindingDB Entry DOI: 10.7270/Q2BK1G7W
					More data for this Ligand-Target Pair
Cyclooxygenase (RAT)	BDBM50012827 (10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE) Show SMILES N1c2ccccc2Oc2ccccc12 Show InChI InChI=1S/C12H9NO/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cells				J Med Chem 33: 2019-24 (1990) BindingDB Entry DOI: 10.7270/Q2G73F9X
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50012827 (10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE) Show SMILES N1c2ccccc2Oc2ccccc12 Show InChI InChI=1S/C12H9NO/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cells				J Med Chem 33: 2019-24 (1990) BindingDB Entry DOI: 10.7270/Q2G73F9X
					More data for this Ligand-Target Pair