BDBM50012887 CHEMBL65430::N-Hydroxy-2-(4-isobutyl-phenyl)-N-methyl-propionamide::N-hydroxy-2-(4-isobutylphenyl)-N-methylpropanamide

SMILES: CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O

InChI Key: InChIKey=LIUJRXOTKOJLOG-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50012887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50012887 (CHEMBL65430 | N-Hydroxy-2-(4-isobutyl-phenyl)-N-me...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O Show InChI InChI=1S/C14H21NO2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15(4)17/h5-8,10-11,17H,9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact RBL-1 cell line				J Med Chem 33: 2070-2 (1990) BindingDB Entry DOI: 10.7270/Q2RJ4HGZ
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50012887 (CHEMBL65430 | N-Hydroxy-2-(4-isobutyl-phenyl)-N-me...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O Show InChI InChI=1S/C14H21NO2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15(4)17/h5-8,10-11,17H,9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	288	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)				J Med Chem 33: 992-8 (1990) BindingDB Entry DOI: 10.7270/Q2WW7GNM
					More data for this Ligand-Target Pair
Cyclooxygenase (RAT)	BDBM50012887 (CHEMBL65430 | N-Hydroxy-2-(4-isobutyl-phenyl)-N-me...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O Show InChI InChI=1S/C14H21NO2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15(4)17/h5-8,10-11,17H,9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell line				J Med Chem 33: 2070-2 (1990) BindingDB Entry DOI: 10.7270/Q2RJ4HGZ
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50012887 (CHEMBL65430 | N-Hydroxy-2-(4-isobutyl-phenyl)-N-me...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O Show InChI InChI=1S/C14H21NO2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15(4)17/h5-8,10-11,17H,9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase in RBL-1 cells				J Med Chem 31: 3-5 (1988) BindingDB Entry DOI: 10.7270/Q2V40T6C
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50012887 (CHEMBL65430 | N-Hydroxy-2-(4-isobutyl-phenyl)-N-me...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O Show InChI InChI=1S/C14H21NO2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15(4)17/h5-8,10-11,17H,9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)				J Med Chem 33: 992-8 (1990) BindingDB Entry DOI: 10.7270/Q2WW7GNM
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50012887 (CHEMBL65430 | N-Hydroxy-2-(4-isobutyl-phenyl)-N-me...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O Show InChI InChI=1S/C14H21NO2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15(4)17/h5-8,10-11,17H,9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cells				J Med Chem 30: 2121-6 (1987) BindingDB Entry DOI: 10.7270/Q29Z93XT
					More data for this Ligand-Target Pair