BDBM50013041 CHEMBL3261385
SMILES: COc1ccc(cc1NC(=S)NC(=O)c1cc2ccccc2o1)C(O)=O
InChI Key: InChIKey=PKATVOJAZAXYKC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human)) | BDBM50013041 (CHEMBL3261385) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 5.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using L-dopachrome methyl ester as substrate incub... | J Med Chem 57: 3737-45 (2014) Article DOI: 10.1021/jm401908w BindingDB Entry DOI: 10.7270/Q2QN68BR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human)) | BDBM50013041 (CHEMBL3261385) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 2.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Covalent inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using 4-hydroxyphenyl pyruvic acid as substrate asses... | Bioorg Med Chem Lett 26: 2764-2767 (2016) BindingDB Entry DOI: 10.7270/Q24X59PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human)) | BDBM50013041 (CHEMBL3261385) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using L-dopachrome methyl ester as substrate incubated for 30 ... | J Med Chem 57: 3737-45 (2014) Article DOI: 10.1021/jm401908w BindingDB Entry DOI: 10.7270/Q2QN68BR | |||||||||||
More data for this Ligand-Target Pair |