BDBM50013140 CHEMBL3262293

SMILES: Cn1c2ccccc2c2cc(CCOc3nccnc3-c3ccncc3)cnc12

InChI Key: InChIKey=HWUIDMFIUXLYEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50013140 (CHEMBL3262293) Show SMILES Cn1c2ccccc2c2cc(CCOc3nccnc3-c3ccncc3)cnc12 Show InChI InChI=1S/C23H19N5O/c1-28-20-5-3-2-4-18(20)19-14-16(15-27-22(19)28)8-13-29-23-21(25-11-12-26-23)17-6-9-24-10-7-17/h2-7,9-12,14-15H,8,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human recombinant PDE10A assessed as substrate hydrolysis using [3H]cAMP as substrate after 30 mins by two-step r...				Bioorg Med Chem Lett 24: 2073-8 (2014) Article DOI: 10.1016/j.bmcl.2014.03.054 BindingDB Entry DOI: 10.7270/Q22V2HNB
					More data for this Ligand-Target Pair