BDBM50013297 CHEMBL149689::N-[4-(5-Methyl-1H-pyrrol-3-yl)-thiazol-2-yl]-guanidine

SMILES: Cc1cc(c[nH]1)-c1csc(N=C(N)N)n1

InChI Key: InChIKey=ZQDQRJJOHRLAJB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase alpha chain 2 (Homo sapiens (Human))	BDBM50013297 (CHEMBL149689 | N-[4-(5-Methyl-1H-pyrrol-3-yl)-thia...) Show SMILES Cc1cc(c[nH]1)-c1csc(N=C(N)N)n1 |(18.9,-14.7,;17.37,-14.88,;16.59,-16.21,;15.08,-15.91,;14.92,-14.38,;16.33,-13.73,;13.86,-16.84,;13.89,-18.36,;12.45,-18.88,;11.52,-17.64,;9.97,-17.68,;9.23,-19.03,;7.69,-19.06,;10.04,-20.34,;12.41,-16.39,)| Show InChI InChI=1S/C9H11N5S/c1-5-2-6(3-12-5)7-4-15-9(13-7)14-8(10)11/h2-4,12H,1H3,(H4,10,11,13,14)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Tested against canine renal Na+/K+ ATPase				J Med Chem 33: 543-52 (1990) BindingDB Entry DOI: 10.7270/Q2K35V79
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/beta chain (Homo sapiens (Human))	BDBM50013297 (CHEMBL149689 | N-[4-(5-Methyl-1H-pyrrol-3-yl)-thia...) Show SMILES Cc1cc(c[nH]1)-c1csc(N=C(N)N)n1 |(18.9,-14.7,;17.37,-14.88,;16.59,-16.21,;15.08,-15.91,;14.92,-14.38,;16.33,-13.73,;13.86,-16.84,;13.89,-18.36,;12.45,-18.88,;11.52,-17.64,;9.97,-17.68,;9.23,-19.03,;7.69,-19.06,;10.04,-20.34,;12.41,-16.39,)| Show InChI InChI=1S/C9H11N5S/c1-5-2-6(3-12-5)7-4-15-9(13-7)14-8(10)11/h2-4,12H,1H3,(H4,10,11,13,14)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPase				J Med Chem 33: 543-52 (1990) BindingDB Entry DOI: 10.7270/Q2K35V79
					More data for this Ligand-Target Pair