BDBM50013389 CHEMBL3263359

SMILES: Cc1ccc(cc1C)C1=NN(C(C1)c1cccc2ccccc12)C1=NC(CS1)c1ccccc1

InChI Key: InChIKey=VLSZZLZNMMNEAM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50013389 (CHEMBL3263359) Show SMILES Cc1ccc(cc1C)C1=NN(C(C1)c1cccc2ccccc12)C1=NC(CS1)c1ccccc1 |t:9,27| Show InChI InChI=1S/C30H27N3S/c1-20-15-16-24(17-21(20)2)27-18-29(26-14-8-12-22-9-6-7-13-25(22)26)33(32-27)30-31-28(19-34-30)23-10-4-3-5-11-23/h3-17,28-29H,18-19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of recombinant his-tagged EGFR (amino acid 645-1186) (unknown origin) expressed in Sf-9 cells after 10 mins by time...				Bioorg Med Chem Lett 24: 2324-8 (2014) Article DOI: 10.1016/j.bmcl.2014.03.072 BindingDB Entry DOI: 10.7270/Q2X63PGR
					More data for this Ligand-Target Pair