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SMILES: COc1ccc(cc1)C1=NN(C(C1)c1ccc2ccccc2c1)C1=NC(=O)CS1

InChI Key: InChIKey=LZCXIOWBIXKXME-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013395   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50013395
PNG
(CHEMBL3263378)
Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc2ccccc2c1)C1=NC(=O)CS1 |t:9,27|
Show InChI InChI=1S/C23H19N3O2S/c1-28-19-10-8-16(9-11-19)20-13-21(26(25-20)23-24-22(27)14-29-23)18-7-6-15-4-2-3-5-17(15)12-18/h2-12,21H,13-14H2,1H3
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MMDB

KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of recombinant his-tagged EGFR (amino acid 645-1186) (unknown origin) expressed in Sf-9 cells after 10 mins by time...

Bioorg Med Chem Lett 24: 2324-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.072
BindingDB Entry DOI: 10.7270/Q2X63PGR
More data for this
Ligand-Target Pair