BDBM50013917 CHEMBL3260532

SMILES: CCOC(=O)C(C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=NCSDOKWVLNDFKG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50013917 (CHEMBL3260532) Show SMILES CCOC(=O)C(C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C25H22F3N3O2/c1-3-33-23(32)24(2,15-17-7-5-4-6-8-17)21-13-14-29-22-20(16-30-31(21)22)18-9-11-19(12-10-18)25(26,27)28/h4-14,16H,3,15H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human GPR119 overexpressed in CHO cells assessed as stimulation of cAMP production by HTRF assay				Bioorg Med Chem Lett 24: 2383-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.023 BindingDB Entry DOI: 10.7270/Q2KP83P1
					More data for this Ligand-Target Pair