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BDBM50013927 5-(4-Methoxy-phenyl)-deca-2,4-dienoic acid (1-methyl-4-pyridin-3-yl-butyl)-amide::CHEMBL95720

SMILES: CCCCC\C(=C/C=C/C(=O)N[C@@H](C)CCCc1cccnc1)c1ccc(OC)cc1

InChI Key: InChIKey=HLCHRSFXEXAMLU-JFIFMDGXSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013927   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50013927
PNG
(5-(4-Methoxy-phenyl)-deca-2,4-dienoic acid (1-meth...)
Show SMILES CCCCC\C(=C/C=C/C(=O)N[C@@H](C)CCCc1cccnc1)c1ccc(OC)cc1
Show InChI InChI=1S/C27H36N2O2/c1-4-5-6-13-24(25-16-18-26(31-3)19-17-25)14-8-15-27(30)29-22(2)10-7-11-23-12-9-20-28-21-23/h8-9,12,14-22H,4-7,10-11,13H2,1-3H3,(H,29,30)/b15-8+,24-14+/t22-/m0/s1
PDB

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PC cid
PC sid
UniChem
PubMed
n/an/a 40n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to platelet activating factor receptor citrate-treated dog blood


J Med Chem 33: 2856-64 (1990)


BindingDB Entry DOI: 10.7270/Q21V5CZJ
More data for this
Ligand-Target Pair