BDBM50014173 CHEMBL3260888

SMILES: CCCC1=C(C(C=C(N1)c1ccccc1)c1ccccc1)C(=O)OCC

InChI Key: InChIKey=BQEPENVGAYBSNO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50014173 (CHEMBL3260888) Show SMILES CCCC1=C(C(C=C(N1)c1ccccc1)c1ccccc1)C(=O)OCC |c:6,t:3| Show InChI InChI=1S/C23H25NO2/c1-3-11-20-22(23(25)26-4-2)19(17-12-7-5-8-13-17)16-21(24-20)18-14-9-6-10-15-18/h5-10,12-16,19,24H,3-4,11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair