BDBM50014300 CHEMBL3260892

SMILES: CCOC(=O)C1=C(C)NC(=CC1c1ccc(C)cc1)c1ccccc1

InChI Key: InChIKey=WVBSXFXYFWMWMR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014300   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium channel (RAT)	BDBM50014300 (CHEMBL3260892) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(C)cc1)c1ccccc1 |c:5,9| Show InChI InChI=1S/C22H23NO2/c1-4-25-22(24)21-16(3)23-20(18-8-6-5-7-9-18)14-19(21)17-12-10-15(2)11-13-17/h5-14,19,23H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50014300 (CHEMBL3260892) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(C)cc1)c1ccccc1 |c:5,9| Show InChI InChI=1S/C22H23NO2/c1-4-25-22(24)21-16(3)23-20(18-8-6-5-7-9-18)14-19(21)17-12-10-15(2)11-13-17/h5-14,19,23H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair