BDBM50014303 CHEMBL3260893

SMILES: CC1=C(C(C=C(N1)c1ccc(Cl)cc1)c1ccccc1)C(=O)OCC=C

InChI Key: InChIKey=FORZUEOUMKFCCC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50014303 (CHEMBL3260893) Show SMILES CC1=C(C(C=C(N1)c1ccc(Cl)cc1)c1ccccc1)C(=O)OCC=C |c:4,t:1| Show InChI InChI=1S/C22H20ClNO2/c1-3-13-26-22(25)21-15(2)24-20(17-9-11-18(23)12-10-17)14-19(21)16-7-5-4-6-8-16/h3-12,14,19,24H,1,13H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair