BDBM50014313 CHEMBL3260894

SMILES: CCOC(=O)C1=C(C)NC(=CC1c1ccc(cc1)[N+]([O-])=O)c1ccccc1

InChI Key: InChIKey=YYVSBISRUIKORF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50014313 (CHEMBL3260894) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(cc1)[N+]([O-])=O)c1ccccc1 |c:5,9| Show InChI InChI=1S/C21H20N2O4/c1-3-27-21(24)20-14(2)22-19(16-7-5-4-6-8-16)13-18(20)15-9-11-17(12-10-15)23(25)26/h4-13,18,22H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair