null

SMILES: OC[C@@H](O)Cn1cnc2cncc(Nc3ccc(I)cc3F)c2c1=O

InChI Key: InChIKey=UNDDRDUPXYCODB-JTQLQIEISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50014417 (CHEMBL3261157) Show SMILES OC[C@@H](O)Cn1cnc2cncc(Nc3ccc(I)cc3F)c2c1=O |r| Show InChI InChI=1S/C16H14FIN4O3/c17-11-3-9(18)1-2-12(11)21-14-5-19-4-13-15(14)16(25)22(8-20-13)6-10(24)7-23/h1-5,8,10,21,23-24H,6-7H2/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of MEK1 (unknown origin)				Bioorg Med Chem Lett 24: 2555-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.086 BindingDB Entry DOI: 10.7270/Q2PG1T73
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50014417 (CHEMBL3261157) Show SMILES OC[C@@H](O)Cn1cnc2cncc(Nc3ccc(I)cc3F)c2c1=O |r| Show InChI InChI=1S/C16H14FIN4O3/c17-11-3-9(18)1-2-12(11)21-14-5-19-4-13-15(14)16(25)22(8-20-13)6-10(24)7-23/h1-5,8,10,21,23-24H,6-7H2/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of MEK1 in human COLO205 cells				Bioorg Med Chem Lett 24: 2555-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.086 BindingDB Entry DOI: 10.7270/Q2PG1T73
					More data for this Ligand-Target Pair