BDBM50014581 CHEMBL3261754

SMILES: Cl.COc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@H]1C(=O)NO)NC(=O)CNC(=O)[C@H](C)N

InChI Key: InChIKey=TZNXAKPMELJCFF-UWSFXBGYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50014581 (CHEMBL3261754) Show SMILES Cl.COc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@H]1C(=O)NO)NC(=O)CNC(=O)[C@H](C)N |r| Show InChI InChI=1S/C17H25N5O7S.ClH/c1-10(18)16(24)19-8-15(23)20-11-7-14(17(25)21-26)22(9-11)30(27,28)13-5-3-12(29-2)4-6-13;/h3-6,10-11,14,26H,7-9,18H2,1-2H3,(H,19,24)(H,20,23)(H,21,25);1H/t10-,11-,14-;/m0./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2 (unknown origin) using succinylated gelatin as substrate preincubated for 10 mins before substrate addition measured after 30 mins...				Bioorg Med Chem 22: 3055-64 (2014) Article DOI: 10.1016/j.bmc.2013.12.025 BindingDB Entry DOI: 10.7270/Q29888JP
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50014581 (CHEMBL3261754) Show SMILES Cl.COc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@H]1C(=O)NO)NC(=O)CNC(=O)[C@H](C)N |r| Show InChI InChI=1S/C17H25N5O7S.ClH/c1-10(18)16(24)19-8-15(23)20-11-7-14(17(25)21-26)22(9-11)30(27,28)13-5-3-12(29-2)4-6-13;/h3-6,10-11,14,26H,7-9,18H2,1-2H3,(H,19,24)(H,20,23)(H,21,25);1H/t10-,11-,14-;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of pig kidney microsomal APN using L-Leu-p-nitroanilide as substrate preincubated for 5 mins before substrate addition measured after 30 m...				Bioorg Med Chem 22: 3055-64 (2014) Article DOI: 10.1016/j.bmc.2013.12.025 BindingDB Entry DOI: 10.7270/Q29888JP
					More data for this Ligand-Target Pair