BDBM50014749 3-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-1H-pyrazole::CHEMBL336708

SMILES: Clc1ccc(cc1)C(c1ccn[nH]1)(c1ccc(Cl)cc1)n1ccnc1

InChI Key: InChIKey=RDGFVGYRNVCDKK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Rattus norvegicus)	BDBM50014749 (3-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-1H-...) Show SMILES Clc1ccc(cc1)C(c1ccn[nH]1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C19H14Cl2N4/c20-16-5-1-14(2-6-16)19(18-9-10-23-24-18,25-12-11-22-13-25)15-3-7-17(21)8-4-15/h1-13H,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair