BDBM50014751 3-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyridine::CHEMBL133026

SMILES: CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccnc1

InChI Key: InChIKey=JEAJDLQMOILVMU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Rattus norvegicus)	BDBM50014751 (3-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyridine | CHE...) Show SMILES CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccnc1 Show InChI InChI=1S/C19H15Cl2N/c1-19(16-3-2-12-22-13-16,14-4-8-17(20)9-5-14)15-6-10-18(21)11-7-15/h2-13H,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	145	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair