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SMILES: Oc1c(F)cc(Cn2cn[nH]c2=S)cc1F

InChI Key: InChIKey=LSGMWEZBYJEOIT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014970   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dopamine beta-hydroxylase


(Bos taurus)		BDBM50014970
PNG
(4-(3,5-Difluoro-4-hydroxy-benzyl)-2,4-dihydro-[1,2...)
Show SMILES Oc1c(F)cc(Cn2cn[nH]c2=S)cc1F
Show InChI InChI=1S/C9H7F2N3OS/c10-6-1-5(2-7(11)8(6)15)3-14-4-12-13-9(14)16/h1-2,4,15H,3H2,(H,13,16)
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n/an/a 35n/an/an/an/an/an/a



Smith Kline & French Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)

J Med Chem 33: 781-9 (1990)


BindingDB Entry DOI: 10.7270/Q2DZ078G
More data for this
Ligand-Target Pair