BDBM50015825 CHEMBL73133::Methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl-amine

SMILES: CNc1nc2ccccc2n2cnnc12

InChI Key: InChIKey=OKMBFCGUSTURFV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Topoisomerase I/II (Homo sapiens (Human))	BDBM50015825 (CHEMBL73133 | Methyl-[1,2,4]triazolo[4,3-a]quinoxa...) Show SMILES CNc1nc2ccccc2n2cnnc12 Show InChI InChI=1S/C10H9N5/c1-11-9-10-14-12-6-15(10)8-5-3-2-4-7(8)13-9/h2-6H,1H3,(H,11,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresis				Eur J Med Chem 155: 117-134 (2018) Article DOI: 10.1016/j.ejmech.2018.06.004 BindingDB Entry DOI: 10.7270/Q2TT4TN9
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50015825 (CHEMBL73133 | Methyl-[1,2,4]triazolo[4,3-a]quinoxa...) Show SMILES CNc1nc2ccccc2n2cnnc12 Show InChI InChI=1S/C10H9N5/c1-11-9-10-14-12-6-15(10)8-5-3-2-4-7(8)13-9/h2-6H,1H3,(H,11,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.				J Med Chem 33: 2240-54 (1990) BindingDB Entry DOI: 10.7270/Q2PR7WKF
					More data for this Ligand-Target Pair