BDBM50016221 CHEMBL3262167

SMILES: Cl.COc1ccc(NC(=O)N2CCNCC2COc2cccnc2)c(OC)c1

InChI Key: InChIKey=AACVZUDANADSGF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50016221 (CHEMBL3262167) Show SMILES Cl.COc1ccc(NC(=O)N2CCNCC2COc2cccnc2)c(OC)c1 Show InChI InChI=1S/C19H24N4O4.ClH/c1-25-15-5-6-17(18(10-15)26-2)22-19(24)23-9-8-21-11-14(23)13-27-16-4-3-7-20-12-16;/h3-7,10,12,14,21H,8-9,11,13H2,1-2H3,(H,22,24);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Critical Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of biotinylated alpha-bungarotoxin binding to alpha7 nAChR in rat PC12 cells by FACS analysis				J Med Chem 57: 3966-83 (2014) Article DOI: 10.1021/jm5004599 BindingDB Entry DOI: 10.7270/Q2CV4K8S
					More data for this Ligand-Target Pair