null

SMILES: COc1ccc(cc1)C(=O)N1CCN(CCOc2ccccc2)CC1

InChI Key: InChIKey=CJXHLCBUPVLQCG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50016307 (CHEMBL3262808) Show SMILES COc1ccc(cc1)C(=O)N1CCN(CCOc2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O3/c1-24-18-9-7-17(8-10-18)20(23)22-13-11-21(12-14-22)15-16-25-19-5-3-2-4-6-19/h2-10H,11-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in HEK293 cells by whole cell patch clamp assay				Eur J Med Chem 81: 89-94 (2014) Article DOI: 10.1016/j.ejmech.2014.03.075 BindingDB Entry DOI: 10.7270/Q2VX0J3N
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50016307 (CHEMBL3262808) Show SMILES COc1ccc(cc1)C(=O)N1CCN(CCOc2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O3/c1-24-18-9-7-17(8-10-18)20(23)22-13-11-21(12-14-22)15-16-25-19-5-3-2-4-6-19/h2-10H,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by ChEMBL					Assay Description Antagonist activity at human D2R expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after 120 min...				J Med Chem 63: 5526-5567 (2020) Article DOI: 10.1021/acs.jmedchem.0c00424
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50016307 (CHEMBL3262808) Show SMILES COc1ccc(cc1)C(=O)N1CCN(CCOc2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O3/c1-24-18-9-7-17(8-10-18)20(23)22-13-11-21(12-14-22)15-16-25-19-5-3-2-4-6-19/h2-10H,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by ChEMBL					Assay Description Agonist activity at human D2R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...				J Med Chem 63: 5526-5567 (2020) Article DOI: 10.1021/acs.jmedchem.0c00424
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50016307 (CHEMBL3262808) Show SMILES COc1ccc(cc1)C(=O)N1CCN(CCOc2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O3/c1-24-18-9-7-17(8-10-18)20(23)22-13-11-21(12-14-22)15-16-25-19-5-3-2-4-6-19/h2-10H,11-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	115	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by ChEMBL					Assay Description Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...				J Med Chem 63: 5526-5567 (2020) Article DOI: 10.1021/acs.jmedchem.0c00424
					More data for this Ligand-Target Pair