BDBM50016611 (6-Oxo-11,12-dihydro-6H-dibenzo[b,f]azocin-5-yl)-acetic acid::CHEMBL274775

SMILES: OC(=O)CN1c2ccccc2CCc2ccccc2C1=O

InChI Key: InChIKey=PPDITWWAUXVIGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (Rattus norvegicus)	BDBM50016611 ((6-Oxo-11,12-dihydro-6H-dibenzo[b,f]azocin-5-yl)-a...) Show SMILES OC(=O)CN1c2ccccc2CCc2ccccc2C1=O Show InChI InChI=1S/C17H15NO3/c19-16(20)11-18-15-8-4-2-6-13(15)10-9-12-5-1-3-7-14(12)17(18)21/h1-8H,9-11H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 10 - 520				J Med Chem 32: 1033-8 (1989) BindingDB Entry DOI: 10.7270/Q2CV4GQC
					More data for this Ligand-Target Pair