BDBM50016642 4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-benzenesulfonamide::CHEMBL279878

SMILES: NS(=O)(=O)c1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O

InChI Key: InChIKey=NRSPCCQAXORBCM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016642 (4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-benzenesu...) Show SMILES NS(=O)(=O)c1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O Show InChI InChI=1S/C9H8ClN3O4S/c10-4-1-2-6(18(11,16)17)5(3-4)7-8(14)13-9(15)12-7/h1-3,14H,(H2,11,16,17)(H2,12,13,15)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair