BDBM50016651 4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-(4-phenyl-butyl)-benzenesulfonamide::CHEMBL19392

SMILES: Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)NCCCCc1ccccc1

InChI Key: InChIKey=VIOMDWSIDKKNSD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016651 (4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-(4-phen...) Show SMILES Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)NCCCCc1ccccc1 Show InChI InChI=1S/C19H20ClN3O4S/c20-14-9-10-16(15(12-14)17-18(24)23-19(25)22-17)28(26,27)21-11-5-4-8-13-6-2-1-3-7-13/h1-3,6-7,9-10,12,21,24H,4-5,8,11H2,(H2,22,23,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair