BDBM50017183 CHEMBL3287359
SMILES: OC(=O)c1ccc2n(Cc3cccc(c3)C(F)(F)F)cnc2c1
InChI Key: InChIKey=JAFOSQHHACGWOK-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-aminolevulinic acid dehydratase (Wolbachia sp. subsp. Brugia malayi (strain TRS)) | BDBM50017183 (CHEMBL3287359) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn Curated by ChEMBL | Assay Description Inhibition of C-terminal His-tagged Wolbachia PBGS using 5-ALA as substrate | J Med Chem 57: 2498-510 (2014) Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-aminolevulinic acid dehydratase (Drosophila melanogaster) | BDBM50017183 (CHEMBL3287359) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn Curated by ChEMBL | Assay Description Inhibition of Drosophila melanogaster recombinant PBGS using 5-ALA as substrate | J Med Chem 57: 2498-510 (2014) Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-aminolevulinic acid dehydratase, chloroplastic (Pisum sativum) | BDBM50017183 (CHEMBL3287359) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn Curated by ChEMBL | Assay Description Inhibition of Pisum sativum PBGS using 5-ALA as substrate | J Med Chem 57: 2498-510 (2014) Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-aminolevulinic acid dehydratase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...) | BDBM50017183 (CHEMBL3287359) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa PAO1 recombinant PBGS using 5-ALA as substrate | J Med Chem 57: 2498-510 (2014) Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-aminolevulinic acid dehydratase (Homo sapiens (Human)) | BDBM50017183 (CHEMBL3287359) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.97E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn Curated by ChEMBL | Assay Description Inhibition of human PBGS using 5-ALA as substrate | J Med Chem 57: 2498-510 (2014) Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 | |||||||||||
More data for this Ligand-Target Pair |