BDBM50017438 4-{4-[4-(2-pyrimidinyl)hexahydro-1-pyrazinyl]butyl}-5-sulfo-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-en-3-one; diHydrochloride::CHEMBL3216644::CHEMBL543246

SMILES: Cl.Cl.O=C1C2C(C3C=CC2C2CC32)S(=O)(=O)N1CCCCN1CCN(CC1)c1ncccn1

InChI Key: InChIKey=ZWOLULVBRWRIAN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017438 (4-{4-[4-(2-pyrimidinyl)hexahydro-1-pyrazinyl]butyl...) Show SMILES Cl.Cl.O=C1C2C(C3C=CC2C2CC32)S(=O)(=O)N1CCCCN1CCN(CC1)c1ncccn1 |c:5,THB:3:4:10.12:8.7,11:10:4.5:8.7,11:12:4.5:8.7| Show InChI InChI=1S/C22H29N5O3S/c28-21-19-15-4-5-16(18-14-17(15)18)20(19)31(29,30)27(21)9-2-1-8-25-10-12-26(13-11-25)22-23-6-3-7-24-22/h3-7,15-20H,1-2,8-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures.				J Med Chem 32: 1024-33 (1989) BindingDB Entry DOI: 10.7270/Q21G0MVD
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