BDBM50017483 5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid [2-methyl-1-(3-methyl-butylcarbamoyl)-propyl]-amide::CHEMBL284228

SMILES: CC(C)CCNC(=O)[C@@H](NC(=O)[C@H](CC(=O)[C@@H](N)CC(C)C)Cc1ccccc1)C(C)C

InChI Key: InChIKey=QZUXJQWIIVGFJI-FIXSFTCYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucyl-cystinyl aminopeptidase (Rattus norvegicus)	BDBM50017483 (5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid [2-m...) Show SMILES CC(C)CCNC(=O)[C@@H](NC(=O)[C@H](CC(=O)[C@@H](N)CC(C)C)Cc1ccccc1)C(C)C Show InChI InChI=1S/C26H43N3O3/c1-17(2)12-13-28-26(32)24(19(5)6)29-25(31)21(15-20-10-8-7-9-11-20)16-23(30)22(27)14-18(3)4/h7-11,17-19,21-22,24H,12-16,27H2,1-6H3,(H,28,32)(H,29,31)/t21-,22-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)				J Med Chem 32: 1378-92 (1989) BindingDB Entry DOI: 10.7270/Q20G3KQ1
					More data for this Ligand-Target Pair
Leucyl-cystinyl aminopeptidase (Rattus norvegicus)	BDBM50017483 (5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid [2-m...) Show SMILES CC(C)CCNC(=O)[C@@H](NC(=O)[C@H](CC(=O)[C@@H](N)CC(C)C)Cc1ccccc1)C(C)C Show InChI InChI=1S/C26H43N3O3/c1-17(2)12-13-28-26(32)24(19(5)6)29-25(31)21(15-20-10-8-7-9-11-20)16-23(30)22(27)14-18(3)4/h7-11,17-19,21-22,24H,12-16,27H2,1-6H3,(H,28,32)(H,29,31)/t21-,22-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Competitive inhibition of leucine aminopeptidase; Ki value reporting the slope effect(Kis)				J Med Chem 32: 1378-92 (1989) BindingDB Entry DOI: 10.7270/Q20G3KQ1
					More data for this Ligand-Target Pair
Aminopeptidase B (Rattus norvegicus)	BDBM50017483 (5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid [2-m...) Show SMILES CC(C)CCNC(=O)[C@@H](NC(=O)[C@H](CC(=O)[C@@H](N)CC(C)C)Cc1ccccc1)C(C)C Show InChI InChI=1S/C26H43N3O3/c1-17(2)12-13-28-26(32)24(19(5)6)29-25(31)21(15-20-10-8-7-9-11-20)16-23(30)22(27)14-18(3)4/h7-11,17-19,21-22,24H,12-16,27H2,1-6H3,(H,28,32)(H,29,31)/t21-,22-,24-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)				J Med Chem 32: 1378-92 (1989) BindingDB Entry DOI: 10.7270/Q20G3KQ1
					More data for this Ligand-Target Pair