BDBM50017601 CHEMBL3288646

SMILES: COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccc(c1)S(N)(=O)=O

InChI Key: InChIKey=PFSOOGFHQCJAQO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017601 (CHEMBL3288646) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccc(c1)S(N)(=O)=O Show InChI InChI=1S/C24H20N4O4S/c1-27-23-14-21(17-6-3-7-18(11-17)32-2)26-28(23)22-13-16(9-10-20(22)24(27)29)15-5-4-8-19(12-15)33(25,30)31/h3-14H,1-2H3,(H2,25,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	696	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017601 (CHEMBL3288646) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccc(c1)S(N)(=O)=O Show InChI InChI=1S/C24H20N4O4S/c1-27-23-14-21(17-6-3-7-18(11-17)32-2)26-28(23)22-13-16(9-10-20(22)24(27)29)15-5-4-8-19(12-15)33(25,30)31/h3-14H,1-2H3,(H2,25,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair