null

SMILES: CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2c(C)nn(C)c12

InChI Key: InChIKey=JTRJPPCZYWBOLW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50017621 (7-Fluoro-1,3-dimethyl-10-(4-methyl-piperazin-1-yl)...) Show SMILES CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2c(C)nn(C)c12 |t:8| Show InChI InChI=1S/C17H21FN6/c1-11-15-16(23(3)21-11)17(24-8-6-22(2)7-9-24)20-14-10-12(18)4-5-13(14)19-15/h4-5,10,19H,6-9H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Limited Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of [3H]QNB binding to Muscarinic acetylcholine receptor from male Olac rat brain.				J Med Chem 32: 2573-82 (1989) BindingDB Entry DOI: 10.7270/Q22F7P2J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017621 (7-Fluoro-1,3-dimethyl-10-(4-methyl-piperazin-1-yl)...) Show SMILES CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2c(C)nn(C)c12 |t:8| Show InChI InChI=1S/C17H21FN6/c1-11-15-16(23(3)21-11)17(24-8-6-22(2)7-9-24)20-14-10-12(18)4-5-13(14)19-15/h4-5,10,19H,6-9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Limited Curated by ChEMBL					Assay Description Inhibition of [3H]spiperone binding to Dopamine receptor D2 from striatum of the rat brain				J Med Chem 32: 2573-82 (1989) BindingDB Entry DOI: 10.7270/Q22F7P2J
					More data for this Ligand-Target Pair