BDBM50017629 6-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL315052

SMILES: CN1CCN(CC1)C1=Nc2ccc(Cl)cc2Nc2nn(C)cc12

InChI Key: InChIKey=UUAXKAADUPQBHB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor (RAT)	BDBM50017629 (6-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4...) Show SMILES CN1CCN(CC1)C1=Nc2ccc(Cl)cc2Nc2nn(C)cc12 |t:8| Show InChI InChI=1S/C16H19ClN6/c1-21-5-7-23(8-6-21)16-12-10-22(2)20-15(12)18-14-9-11(17)3-4-13(14)19-16/h3-4,9-10H,5-8H2,1-2H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Limited Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of [3H]QNB binding to Muscarinic acetylcholine receptor from male Olac rat brain.				J Med Chem 32: 2573-82 (1989) BindingDB Entry DOI: 10.7270/Q22F7P2J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017629 (6-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4...) Show SMILES CN1CCN(CC1)C1=Nc2ccc(Cl)cc2Nc2nn(C)cc12 |t:8| Show InChI InChI=1S/C16H19ClN6/c1-21-5-7-23(8-6-21)16-12-10-22(2)20-15(12)18-14-9-11(17)3-4-13(14)19-16/h3-4,9-10H,5-8H2,1-2H3,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Limited Curated by ChEMBL					Assay Description Inhibition of [3H]spiperone binding to Dopamine receptor D2 from striatum of the rat brain				J Med Chem 32: 2573-82 (1989) BindingDB Entry DOI: 10.7270/Q22F7P2J
					More data for this Ligand-Target Pair