BDBM50017633 10-(4-Cyclopropylmethyl-piperazin-1-yl)-7-fluoro-2-methyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL87869

SMILES: Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(CC3CC3)CC2)n1

InChI Key: InChIKey=ZEBMXWFZKAPFND-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor (RAT)	BDBM50017633 (10-(4-Cyclopropylmethyl-piperazin-1-yl)-7-fluoro-2...) Show SMILES Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(CC3CC3)CC2)n1 |c:14| Show InChI InChI=1S/C19H23FN6/c1-24-12-15-18(23-24)21-16-5-4-14(20)10-17(16)22-19(15)26-8-6-25(7-9-26)11-13-2-3-13/h4-5,10,12-13H,2-3,6-9,11H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Limited Curated by ChEMBL					Assay Description The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase II				J Med Chem 32: 2573-82 (1989) BindingDB Entry DOI: 10.7270/Q22F7P2J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017633 (10-(4-Cyclopropylmethyl-piperazin-1-yl)-7-fluoro-2...) Show SMILES Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(CC3CC3)CC2)n1 |c:14| Show InChI InChI=1S/C19H23FN6/c1-24-12-15-18(23-24)21-16-5-4-14(20)10-17(16)22-19(15)26-8-6-25(7-9-26)11-13-2-3-13/h4-5,10,12-13H,2-3,6-9,11H2,1H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Limited Curated by ChEMBL					Assay Description Inhibition of [3H]spiperone binding to Dopamine receptor D2 from striatum of the rat brain				J Med Chem 32: 2573-82 (1989) BindingDB Entry DOI: 10.7270/Q22F7P2J
					More data for this Ligand-Target Pair