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SMILES: CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2c(C)n(C)nc12

InChI Key: InChIKey=ZVOOGDDDAQCDTD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017649   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50017649
PNG
(7-Fluoro-2,3-dimethyl-10-(4-methyl-piperazin-1-yl)...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2c(C)n(C)nc12 |t:8|
Show InChI InChI=1S/C17H21FN6/c1-11-15-16(21-23(11)3)17(24-8-6-22(2)7-9-24)20-14-10-12(18)4-5-13(14)19-15/h4-5,10,19H,6-9H2,1-3H3
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Similars
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Lilly Research Centre Limited

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to Dopamine receptor D2 from striatum of the rat brain

J Med Chem 32: 2573-82 (1989)


BindingDB Entry DOI: 10.7270/Q22F7P2J
More data for this
Ligand-Target Pair