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BDBM50018371 5,5-Bis-(3-fluoro-phenyl)-penta-2,4-dienoic acid (4-pyridin-3-yl-butyl)-amide::CHEMBL52834

SMILES: Fc1cccc(c1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1cccc(F)c1

InChI Key: InChIKey=XMGXYXVSTYXTSE-LHHJGKSTSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018371   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018371
PNG
(5,5-Bis-(3-fluoro-phenyl)-penta-2,4-dienoic acid (...)
Show SMILES Fc1cccc(c1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1cccc(F)c1
Show InChI InChI=1S/C26H24F2N2O/c27-23-11-3-9-21(17-23)25(22-10-4-12-24(28)18-22)13-5-14-26(31)30-16-2-1-7-20-8-6-15-29-19-20/h3-6,8-15,17-19H,1-2,7,16H2,(H,30,31)/b14-5+
PDB

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n/an/a 20n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair