BDBM50018522 6,10,15,19-Tetramethyl-tetracosa-6,10,14,18-tetraene-1,23-diyne-3,22-diol::CHEMBL67458
SMILES: C\C(CC\C=C(/C)CCC(O)C#C)=C/CC\C=C(/C)CC\C=C(/C)CCC(O)C#C
InChI Key: InChIKey=KLCLKOLLZKAMSI-TXLDAEQNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Squalene monooxygenase (Homo sapiens (Human)) | BDBM50018522 (6,10,15,19-Tetramethyl-tetracosa-6,10,14,18-tetrae...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Curated by ChEMBL | Assay Description Inhibitory activity against Candida albicans Squalene Epoxidase | J Med Chem 32: 2152-8 (1989) BindingDB Entry DOI: 10.7270/Q21835HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene monooxygenase (Homo sapiens (Human)) | BDBM50018522 (6,10,15,19-Tetramethyl-tetracosa-6,10,14,18-tetrae...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Curated by ChEMBL | Assay Description Inhibitory activity against Squalene Epoxidase in pig liver | J Med Chem 32: 2152-8 (1989) BindingDB Entry DOI: 10.7270/Q21835HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50018522 (6,10,15,19-Tetramethyl-tetracosa-6,10,14,18-tetrae...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase in pig liver | J Med Chem 32: 2152-8 (1989) BindingDB Entry DOI: 10.7270/Q21835HM | |||||||||||
More data for this Ligand-Target Pair |