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SMILES: CCN1CCN(CC1)C(=O)c1sc2c([nH]c(=O)c3ccccc23)c1C

InChI Key: InChIKey=WXFGNEQQWVQXJG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018700   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50018700
PNG
(CHEMBL3291331)
Show SMILES CCN1CCN(CC1)C(=O)c1sc2c([nH]c(=O)c3ccccc23)c1C
Show InChI InChI=1S/C19H21N3O2S/c1-3-21-8-10-22(11-9-21)19(24)16-12(2)15-17(25-16)13-6-4-5-7-14(13)18(23)20-15/h4-7H,3,8-11H2,1-2H3,(H,20,23)
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Similars
Article
PubMed
n/an/a 79n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PARP-1 after 1 hr by ELISA

Bioorg Med Chem Lett 24: 2669-73 (2014)


Article DOI: 10.1016/j.bmcl.2014.04.061
BindingDB Entry DOI: 10.7270/Q2ZC84FM
More data for this
Ligand-Target Pair