BDBM50018897 CHEMBL3287081

SMILES: COc1cc(CC(O)=O)ccc1Oc1ccc2n(C)ccc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=LTUVCSMNZGLAPS-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50018897 (CHEMBL3287081) Show SMILES COc1cc(CC(O)=O)ccc1Oc1ccc2n(C)ccc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H20Cl2N2O6S/c1-28-10-9-16-18(28)5-7-20(34-19-6-3-14(12-23(29)30)11-21(19)33-2)24(16)27-35(31,32)22-8-4-15(25)13-17(22)26/h3-11,13,27H,12H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK293 cells in buffer solution with 0.5% bovine serum albumin by scintillation counting				Bioorg Med Chem Lett 24: 2877-80 (2014) Article DOI: 10.1016/j.bmcl.2014.04.092 BindingDB Entry DOI: 10.7270/Q25X2BGN
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50018897 (CHEMBL3287081) Show SMILES COc1cc(CC(O)=O)ccc1Oc1ccc2n(C)ccc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H20Cl2N2O6S/c1-28-10-9-16-18(28)5-7-20(34-19-6-3-14(12-23(29)30)11-21(19)33-2)24(16)27-35(31,32)22-8-4-15(25)13-17(22)26/h3-11,13,27H,12H2,1-2H3,(H,29,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human DP receptor expressed in HEK293 cells in presence of 50% human plasma by scintillation counting				Bioorg Med Chem Lett 24: 2877-80 (2014) Article DOI: 10.1016/j.bmcl.2014.04.092 BindingDB Entry DOI: 10.7270/Q25X2BGN
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50018897 (CHEMBL3287081) Show SMILES COc1cc(CC(O)=O)ccc1Oc1ccc2n(C)ccc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H20Cl2N2O6S/c1-28-10-9-16-18(28)5-7-20(34-19-6-3-14(12-23(29)30)11-21(19)33-2)24(16)27-35(31,32)22-8-4-15(25)13-17(22)26/h3-11,13,27H,12H2,1-2H3,(H,29,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human DP receptor expressed in HEK293 cells in buffer solution with 0.5% bovine serum albumin by scintillation countin...				Bioorg Med Chem Lett 24: 2877-80 (2014) Article DOI: 10.1016/j.bmcl.2014.04.092 BindingDB Entry DOI: 10.7270/Q25X2BGN
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50018897 (CHEMBL3287081) Show SMILES COc1cc(CC(O)=O)ccc1Oc1ccc2n(C)ccc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H20Cl2N2O6S/c1-28-10-9-16-18(28)5-7-20(34-19-6-3-14(12-23(29)30)11-21(19)33-2)24(16)27-35(31,32)22-8-4-15(25)13-17(22)26/h3-11,13,27H,12H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK293 cells in presence of 50% human plasma by scintillation counting				Bioorg Med Chem Lett 24: 2877-80 (2014) Article DOI: 10.1016/j.bmcl.2014.04.092 BindingDB Entry DOI: 10.7270/Q25X2BGN
					More data for this Ligand-Target Pair