BDBM50019064 CHEMBL3288340

SMILES: FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1nccs1

InChI Key: InChIKey=GRQGVAJGHITNBZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019064 (CHEMBL3288340) Show SMILES FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1nccs1 Show InChI InChI=1S/C16H15F3N2OS/c17-16(18,19)13-4-2-1-3-12(13)11-5-8-21(9-6-11)15(22)14-20-7-10-23-14/h1-4,7,10-11H,5-6,8-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019064 (CHEMBL3288340) Show SMILES FC(F)(F)c1ccccc1C1CCN(CC1)C(=O)c1nccs1 Show InChI InChI=1S/C16H15F3N2OS/c17-16(18,19)13-4-2-1-3-12(13)11-5-8-21(9-6-11)15(22)14-20-7-10-23-14/h1-4,7,10-11H,5-6,8-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair