BDBM50019303 CHEMBL3289408

SMILES: CS(=O)(=O)CCNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O

InChI Key: InChIKey=HVPNYGPYDGPRDO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50019303 (CHEMBL3289408) Show SMILES CS(=O)(=O)CCNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O Show InChI InChI=1S/C20H17N3O4S/c1-28(26,27)10-8-21-19(24)15-7-4-9-23-18(15)22-17-12-14-6-3-2-5-13(14)11-16(17)20(23)25/h2-7,9,11-12H,8,10H2,1H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysis				J Med Chem 57: 4950-61 (2014) Article DOI: 10.1021/jm5004842 BindingDB Entry DOI: 10.7270/Q2M0470M
					More data for this Ligand-Target Pair