BDBM50019318 CHEMBL3289423

SMILES: CC(CN(C)C)NC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O

InChI Key: InChIKey=NAZSUSPAXCYQQA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50019318 (CHEMBL3289423) Show SMILES CC(CN(C)C)NC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O Show InChI InChI=1S/C22H22N4O2/c1-14(13-25(2)3)23-21(27)17-9-6-10-26-20(17)24-19-12-16-8-5-4-7-15(16)11-18(19)22(26)28/h4-12,14H,13H2,1-3H3,(H,23,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysis				J Med Chem 57: 4950-61 (2014) Article DOI: 10.1021/jm5004842 BindingDB Entry DOI: 10.7270/Q2M0470M
					More data for this Ligand-Target Pair