BDBM50019320 CHEMBL3289425

SMILES: CC(C)N(CCNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O)C(C)C

InChI Key: InChIKey=UTMWPORTWADFBY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50019320 (CHEMBL3289425) Show SMILES CC(C)N(CCNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O)C(C)C Show InChI InChI=1S/C25H28N4O2/c1-16(2)28(17(3)4)13-11-26-24(30)20-10-7-12-29-23(20)27-22-15-19-9-6-5-8-18(19)14-21(22)25(29)31/h5-10,12,14-17H,11,13H2,1-4H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysis				J Med Chem 57: 4950-61 (2014) Article DOI: 10.1021/jm5004842 BindingDB Entry DOI: 10.7270/Q2M0470M
					More data for this Ligand-Target Pair