BDBM50019323 CHEMBL3289428

SMILES: COCCN(C)CCNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O

InChI Key: InChIKey=UIZOCZLARAMGLG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50019323 (CHEMBL3289428) Show SMILES COCCN(C)CCNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O Show InChI InChI=1S/C23H24N4O3/c1-26(12-13-30-2)11-9-24-22(28)18-8-5-10-27-21(18)25-20-15-17-7-4-3-6-16(17)14-19(20)23(27)29/h3-8,10,14-15H,9,11-13H2,1-2H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysis				J Med Chem 57: 4950-61 (2014) Article DOI: 10.1021/jm5004842 BindingDB Entry DOI: 10.7270/Q2M0470M
					More data for this Ligand-Target Pair