BDBM50019325 CHEMBL160057

SMILES: CN(C)CCNC(=O)c1cccn2c1nc1ccccc1c2=O

InChI Key: InChIKey=HKOLFXDCHCCSCT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50019325 (CHEMBL160057) Show SMILES CN(C)CCNC(=O)c1cccn2c1nc1ccccc1c2=O Show InChI InChI=1S/C17H18N4O2/c1-20(2)11-9-18-16(22)13-7-5-10-21-15(13)19-14-8-4-3-6-12(14)17(21)23/h3-8,10H,9,11H2,1-2H3,(H,18,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysis				J Med Chem 57: 4950-61 (2014) Article DOI: 10.1021/jm5004842 BindingDB Entry DOI: 10.7270/Q2M0470M
					More data for this Ligand-Target Pair