BDBM50019396 4-(2-Dipropylamino-ethyl)-benzene-1,2-diol::4-(2-Dipropylamino-ethyl)-benzene-1,2-diol (N,N-dipropyldopamine)::CHEMBL15564::N,N-di-n-Propyldopamine

SMILES: CCCN(CCC)CCc1ccc(O)c(O)c1

InChI Key: InChIKey=LMYSNFBROWBKMB-UHFFFAOYSA-N

Data: 8 KI  1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50019396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against Dopamine receptor D2 in rat striatal membranes using [3H]spiperone				Citation and Details BindingDB Entry DOI: 10.7270/Q2930WC4
					More data for this Ligand-Target Pair
DRD2 (RABBIT)	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP Ki Database									J Pharmacol Exp Ther 227: 592-9 (1983) BindingDB Entry DOI: 10.7270/Q2902291
					More data for this Ligand-Target Pair
DRD2 (RABBIT)	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP Ki Database									J Pharmacol Exp Ther 227: 592-9 (1983) BindingDB Entry DOI: 10.7270/Q2902291
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP Ki Database									J Pharmacol Exp Ther 227: 592-9 (1983) BindingDB Entry DOI: 10.7270/Q2902291
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP Ki Database									J Pharmacol Exp Ther 227: 592-9 (1983) BindingDB Entry DOI: 10.7270/Q2902291
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-1 (Homo sapiens (Human))	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for its binding affinity against Alpha-1 adrenergic receptor				Citation and Details BindingDB Entry DOI: 10.7270/Q2930WC4
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars		4.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against Dopamine receptor D1 in rat striatal membranes using [3H]SCH-23390				Citation and Details BindingDB Entry DOI: 10.7270/Q2930WC4
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Rattus norvegicus)	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars		<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for its binding affinity against Alpha-2 adrenergic receptor				Citation and Details BindingDB Entry DOI: 10.7270/Q2930WC4
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for dopamine agonist activity in rabbit ear artery after at a dose of 3 mg/kg				J Med Chem 26: 933-5 (1983) BindingDB Entry DOI: 10.7270/Q2F76FRK
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes				J Med Chem 30: 1166-76 (1987) BindingDB Entry DOI: 10.7270/Q2028QJ6
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50019396 (4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...) Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1 Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of peptide EPQ (pY) EEIPI binding to Fyn protein kinase SH2 domain at 100 uM (no inhibition)				Bioorg Med Chem Lett 7: 113-116 (1997) Article DOI: 10.1016/S0960-894X(96)00589-6 BindingDB Entry DOI: 10.7270/Q2H41RFZ
					More data for this Ligand-Target Pair