null

SMILES: NS(=O)(=O)c1cc(NC(=O)Nn2ccc3ccccc23)c(Cl)cc1Cl

InChI Key: InChIKey=PGWLRTGRYZCONI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50019534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50019534 (CHEMBL3291102) Show SMILES NS(=O)(=O)c1cc(NC(=O)Nn2ccc3ccccc23)c(Cl)cc1Cl Show InChI InChI=1S/C15H12Cl2N4O3S/c16-10-7-11(17)14(25(18,23)24)8-12(10)19-15(22)20-21-6-5-9-3-1-2-4-13(9)21/h1-8H,(H2,18,23,24)(H2,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydra...				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50019534 (CHEMBL3291102) Show SMILES NS(=O)(=O)c1cc(NC(=O)Nn2ccc3ccccc23)c(Cl)cc1Cl Show InChI InChI=1S/C15H12Cl2N4O3S/c16-10-7-11(17)14(25(18,23)24)8-12(10)19-15(22)20-21-6-5-9-3-1-2-4-13(9)21/h1-8H,(H2,18,23,24)(H2,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydr...				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50019534 (CHEMBL3291102) Show SMILES NS(=O)(=O)c1cc(NC(=O)Nn2ccc3ccccc23)c(Cl)cc1Cl Show InChI InChI=1S/C15H12Cl2N4O3S/c16-10-7-11(17)14(25(18,23)24)8-12(10)19-15(22)20-21-6-5-9-3-1-2-4-13(9)21/h1-8H,(H2,18,23,24)(H2,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50019534 (CHEMBL3291102) Show SMILES NS(=O)(=O)c1cc(NC(=O)Nn2ccc3ccccc23)c(Cl)cc1Cl Show InChI InChI=1S/C15H12Cl2N4O3S/c16-10-7-11(17)14(25(18,23)24)8-12(10)19-15(22)20-21-6-5-9-3-1-2-4-13(9)21/h1-8H,(H2,18,23,24)(H2,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair