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SMILES: O=C(OCC(C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)N1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1

InChI Key: InChIKey=NWVNPWZUKXKBRN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019842   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50019842
PNG
(CHEMBL3286908)
Show SMILES O=C(OCC(C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)N1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C39H41N7O2/c47-39(44-25-23-43(24-26-44)38-42-32-15-7-9-17-34(32)45(38)27-29-11-3-1-4-12-29)48-28-36(30-19-21-40-22-20-30)46-35-18-10-8-16-33(35)41-37(46)31-13-5-2-6-14-31/h1-18,30,36,40H,19-28H2
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KEGG

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 35n/an/an/an/an/a



Max Planck Institute of Molecular Physiology

Curated by ChEMBL


Assay Description
Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay

J Med Chem 57: 5435-48 (2014)


Article DOI: 10.1021/jm500632s
BindingDB Entry DOI: 10.7270/Q24Q7WJP
More data for this
Ligand-Target Pair