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BDBM50019845 CHEMBL3286911

SMILES: O=C(OC[C@H](C1CCNCC1)n1c(nc2ccccc12)C1CC1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1

InChI Key: InChIKey=YKMHGUCILDTIEK-JGCGQSQUSA-N

Data: 1 Kd

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019845   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50019845
PNG
(CHEMBL3286911)
Show SMILES O=C(OC[C@H](C1CCNCC1)n1c(nc2ccccc12)C1CC1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1 |r|
Show InChI InChI=1S/C35H40N6O2S/c42-34(27-13-18-39(19-14-27)35-38-28-5-1-3-7-30(28)40(35)21-24-15-20-44-23-24)43-22-32(25-11-16-36-17-12-25)41-31-8-4-2-6-29(31)37-33(41)26-9-10-26/h1-8,15,20,23,25-27,32,36H,9-14,16-19,21-22H2/t32-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 12n/an/an/an/an/a



Max Planck Institute of Molecular Physiology

Curated by ChEMBL


Assay Description
Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay

J Med Chem 57: 5435-48 (2014)


Article DOI: 10.1021/jm500632s
BindingDB Entry DOI: 10.7270/Q24Q7WJP
More data for this
Ligand-Target Pair