null

SMILES: CS(=O)(=O)NC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1ccc2N(CCOc2c1)C(=O)Nc1ccccc1

InChI Key: InChIKey=PQJJLSFCANBFSI-HZCBDIJESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM50020074 (CHEMBL3287888) Show SMILES CS(=O)(=O)NC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1ccc2N(CCOc2c1)C(=O)Nc1ccccc1 |r,wU:11.14,wD:8.7,(24.03,-4.14,;22.72,-4.94,;21.23,-5.33,;21.63,-3.84,;22.76,-6.48,;21.44,-7.28,;20.09,-6.54,;21.48,-8.82,;20.17,-9.62,;18.81,-8.88,;17.5,-9.67,;17.54,-11.21,;18.89,-11.95,;20.2,-11.15,;16.22,-12.01,;14.87,-11.27,;13.56,-12.07,;13.6,-13.61,;14.95,-14.35,;16.26,-13.55,;12.28,-14.41,;12.32,-15.95,;11.01,-16.75,;9.65,-16.01,;8.34,-16.81,;6.99,-16.07,;6.95,-14.53,;8.27,-13.73,;9.62,-14.47,;10.93,-13.67,;8.38,-18.35,;9.72,-19.08,;7.06,-19.15,;7.1,-20.69,;5.78,-21.48,;5.82,-23.02,;7.17,-23.76,;8.49,-22.95,;8.45,-21.42,)| Show InChI InChI=1S/C30H33N3O5S/c1-39(36,37)32-29(34)19-21-7-9-22(10-8-21)23-11-13-24(14-12-23)25-15-16-27-28(20-25)38-18-17-33(27)30(35)31-26-5-3-2-4-6-26/h2-6,11-16,20-22H,7-10,17-19H2,1H3,(H,31,35)(H,32,34)/t21-,22-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50020074 (CHEMBL3287888) Show SMILES CS(=O)(=O)NC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1ccc2N(CCOc2c1)C(=O)Nc1ccccc1 |r,wU:11.14,wD:8.7,(24.03,-4.14,;22.72,-4.94,;21.23,-5.33,;21.63,-3.84,;22.76,-6.48,;21.44,-7.28,;20.09,-6.54,;21.48,-8.82,;20.17,-9.62,;18.81,-8.88,;17.5,-9.67,;17.54,-11.21,;18.89,-11.95,;20.2,-11.15,;16.22,-12.01,;14.87,-11.27,;13.56,-12.07,;13.6,-13.61,;14.95,-14.35,;16.26,-13.55,;12.28,-14.41,;12.32,-15.95,;11.01,-16.75,;9.65,-16.01,;8.34,-16.81,;6.99,-16.07,;6.95,-14.53,;8.27,-13.73,;9.62,-14.47,;10.93,-13.67,;8.38,-18.35,;9.72,-19.08,;7.06,-19.15,;7.1,-20.69,;5.78,-21.48,;5.82,-23.02,;7.17,-23.76,;8.49,-22.95,;8.45,-21.42,)| Show InChI InChI=1S/C30H33N3O5S/c1-39(36,37)32-29(34)19-21-7-9-22(10-8-21)23-11-13-24(14-12-23)25-15-16-27-28(20-25)38-18-17-33(27)30(35)31-26-5-3-2-4-6-26/h2-6,11-16,20-22H,7-10,17-19H2,1H3,(H,31,35)(H,32,34)/t21-,22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair